Feed Additives Needed to Combat Multiple Mycotoxin Presence: Takeaway from 8th World Mycotoxin Forum
The rationale for using feed additives to combat the multi-mycotoxin occurrence in animal feedstock emerged during the eighth World Mycotoxin Forum that ran 10-12 November.
Around 400 individuals including agrifood professionals, regulatory authorities, consultants and academics representing over 30 countries attended this year s World Mycotoxin Forum.
Vienna, 13 November 2014 Dr. Jaume Galobart of the European Food Safety Authority s Feed Unit addressed the need for feed additives to combat the presence of mycotoxins fungal metabolites toxic to animals and humans at levels considered safe e.g. below maximum regulatory thresholds.
维也纳，2014年11月13日 欧洲食品安全局食品单元的Jaume Galobart博士强调了使用饲料添加剂去对抗霉菌毒素(对动物和人类均有毒性的真菌代谢产物)的必要性 即便是在被认为是 安全 的毒素含量水平下，例如低于法规设定的最高限值。
First, Dr. Galobart emphasized that EFSA recommendations regarding mycotoxin levels do not take co-contamination the presence of multiple mycotoxins into consideration. Multiple mycotoxin presence can have a compound, negative impact on both humans and animals. According to Dr. Isabelle Oswald at the French National Institute for Agricultural Research (INRA), The type of mycotoxin interaction depends on the dose. In the case of [mycotoxin] deoxynivalenol (DON) and acetyl DON, the synergistic effect is observed at low dosage levels.
首先，Galobart博士强调了EFSA (欧洲食品安全局)所建议的霉菌毒素含量水平并未考虑共污染 多种霉菌毒素都存在的情况。多种霉菌毒素的共同存在对人和动物都会产生复合的负面的影响。法国农业国家研究所的Isabelle Oswald博士提出 霉菌毒素的相互作用类型与剂量相关。脱氧雪腐镰刀菌烯醇(呕吐毒素 DON)和乙酰脱氧雪腐镰刀菌烯醇之间的协同效应在低剂量水平就能观察到。 。
Co-exposure is the norm not the exception, declared Dr. J. David Miller, professor at Carleton University in Canada. Indeed, the most recent Global Mycotoxin Survey conducted by Biomin indicates that 48% of feedstock samples taken worldwide are contaminated by more than one mycotoxin.
同时暴露于多种霉菌毒素是普遍的 并非个例 加拿大Carleton大学的J. David Miller J. David Miller 教授声明。实际上，百奥明最新的全球霉菌毒素调查显示取自世界各地的饲料样品中有48%的样品存在多于一种的霉菌毒素污染。
Second, Dr. Galobart pointed to instances in which mycotoxin levels in feedstock that initially fall within an acceptable range are transformed during animals digestion, producing metabolites that can exceed regulatory limits as in the case of aflatoxin M1, found in the milk of lactating cows fed allowed levels of aflatoxin B1. M1 has a potential carryover level in milk of anywhere from 1 to 6 percent.
其次，Galobart博士指出有些情况下饲料中的霉菌毒素水平起初是在允许范围内的，但经过动物的消化而转化产生了超过法规上限的代谢产物 正如黄曲霉毒素M1的例子，产奶牛被饲喂的是黄曲霉毒素B1水平合格的饲料也会发生牛奶中M1超标的情况。牛奶中M1 的残留水平约为饲料中黄曲霉毒素B1水平的1-6%。
Combating the harmful effects posed by mycotoxins is essential for animal health, performance and food safety. Dr. Dieter Moll, Research Team Leader - Molecular Biology at Biomin, surveyed the current state and future perspectives for mycotoxin deactivation through enzymatic biotransformation in which enzymes break down mycotoxins into less harmful substances.
In particular, he cited FUMzyme the first-ever purified enzyme authorized by the EU proven to biotransform fumonisins into non-toxic metabolites originally identified by Biomin Research Center. The enzyme is effective in degrading fumonisins (a mycotoxin derived from Fusarium) into compounds of significantly lower toxicity in the gastrointestinal tract of animals.
他特别提到FUMzyme (烟曲霉毒素降解酶) 首个通过欧盟官方认证的纯化的酶，它能将烟曲霉毒素通过生物转化降解为无毒的代谢产物 源于百奥明研究中心的分离鉴定。
Biomin and Romer Labs both part of Erber Group were gold sponsor of the World Mycotoxin Forum.
百奥明和罗马实验室 同属于Erber 集团 都是本次世界霉菌毒素论坛的金牌赞助商。
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BIOMIN, a leading company focusing on health in animal nutrition, develops and produces feed additives, premixes and services to improve animal health and performance, in an economically viable way. Leveraging on the latest technologies and extensive R D programs, BIOMIN offers sustainable quality products which include solutions for mycotoxin risk management, a groundbreaking natural growth promoting concept as well as other specific solutions which address dietary requirements for swine, poultry, dairy and aquaculture.